How gluten can cause depression, anxiety, brain fog when you have Hashimoto’s hypothyroidism

Do you have Hashimoto’s hypothyroidism and suffer from depression, anxiety disorders, brain fog, memory loss, or other brain-based issues?

While conventional medicine turns to drug treatments, recent research points to poor gut health as the root of mental illness. This is because inflammation in the gut triggers inflammation throughout the body, including in the brain, bringing on depression, anxiety, brain fog, memory loss and other neurological symptoms. Although many factors affect gut health—and hence brain health—one of the more profound is a sensitivity to gluten, the protein found in wheat, barley, rye, and other wheat-like grains. In fact, a gluten sensitivity has been found to affect brain and nerve tissue more than any other tissue in the body.

Gluten sensitivity once was thought to be limited to celiac disease, an autoimmune response to gluten that damages the digestive tract and is linked to depression. However, newer research has confirmed the validity of non-celiac gluten sensitivity, an immune response to gluten that causes many symptoms, including digestive problems, skin rashes, joint pain, and neurological and psychiatric diseases. Recent research shows gluten degenerates brain and nervous tissue in a significant portion of those with gluten sensitivity.

A gluten-free diet is important for those with Hashimoto’s hypothyroidism as a number of studies show a link between gluten sensitivity and Hashimoto’s, as well as other autoimmune reactions.

How Does Gluten Affect Mental Health?

Beyond exacerbating Hashimoto’s hypothyroidism, gluten can affect mental health in a variety of ways.

For instance, gluten sensitivity can lead to depression, anxiety, brain fog and other brain symptoms by irritating the lining of the small intestine, resulting in “leaky gut,” a condition in which the intestinal wall becomes overly porous. This allows undigested food, toxins and bacteria into the bloodstream where they trigger inflammation throughout the body and brain. Also, certain harmful bacteria that travel through a leaky gut into the bloodstream release toxic molecules (lipopolysaccharides) that are linked to depression and various psychiatric disorders.

Another way gluten can trigger depression is through gluten cross-reactivity. Because gluten is similar in structure to brain tissue, when the immune system attacks gluten in the blood, it can confuse brain tissue with gluten and accidentally attack brain and nerve tissue as well.

Gluten is also known to disrupt the balance of good and bad bacteria in the digestive tract. There is a relationship between gut bacteria and the brain, and an imbalance in gut bacteria has been linked with psychiatric disorders.

The gut damage caused by a gluten sensitivity can also prevent the absorption of nutrients essential for brain health, especially zinc, tryptophan, and B vitamins. These nutrients are critical for the synthesis of brain chemicals that prevent depression, anxiety and other brain-based disorders.

What Steps Can You Take When You Have Hashimoto’s Hypothyroidism?

If you are experiencing depression, anxiety, brain fog, memory loss, or other unresolved brain-based issues, testing for gluten sensitivity can be a valuable tool in knowing how best to manage it. Addressing leaky gut is also paramount.

Ask my office for more information on leaky gut and the connection between gluten and Hashimoto’s hypothyroidism, depression, anxiety, brain fog, memory loss, and other brain-based disorders.

Dr. Joni Labbe

About Dr. Joni Labbe

Dr. Joni Labbe is a board-certified clinical nutritionist specializing in science-based nutrition with a focus on women's health issues. She has successfully helped pre-menopausal and menopausal women regain and maintain their health since 1995. Dr. Labbe is the author of the Amazon #1 Best Selling book Thyroid & Menopause Madness and It’s Not Just Menopause: It’s Your Thyroid. She is also a professional speaker, radio personality, fitness expert, and former host of “Healthier Way With Dr. Labbe.” Dr. Labbe is one of the country’s leading authorities on thyroid disorders, including Hashimoto’s disease. Dr. Labbe has also authored numerous articles and blogs on health, nutrition, and thyroid health, as seen in Naturally Savvy, Thyroid Nation, and Fox News. She is a Board Certified Clinical Nutritionalist, Doctor of Chiropractic, and has post graduate training in Functional Neurology, Functional Endocrinology, Functional Blood Chemistry Analysis, and earned a Diplomate and Fellow in Nutrition from the American Association of Integrative Medicine.

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